-
Featured Solutions
-
Related Resources
-
Related Services
Featured Solutions
-
DMPK Compound Management Services
WuXi AppTec DMPK compound management platform integrates automatic storage devices and compound management systems to provide safe and accurate compound management services.
-
Metabolite Biosynthesis and Structural Characterization
The biosynthesis platform of WuXi AppTec DMPK can biosynthesize target metabolites by in vitro or in vivo approach based on study result of MetID, and combination with preparative liquid chromatograph for separation, high-resolution mass spectrometry (HRMS) and nuclear magnetic resonance (NMR) for structural characterization.
-
Radiolabeled Compound Synthesis
WuXi AppTec DMPK offers radiolabeling services to clients worldwide using carbon-14 and Hydrogen-3. We offer customized radiolabeling services to suit a wide variety of research needs.
-
High-Throughput Automation Platforms
We have successfully validated and deployed several high-throughput automation platforms, including in vitro ADME high-throughput integrated automated workstation, and biological sample pre-treatment full-automation system, etc. to reduce the human error, improve data quality, and shorten the turnaround time, thus accelerating clients’ development process.
Start your study
Related Resources
-
Decoding Peptide ADME Challenges: Integrated Radiolabeled Synthesis & ADME Platform - DMPK Frontiers
VideosOct 24, 2025Learn More
-
Approved Ophthalmic Protein Drugs and Their Preclinical Pharmacokinetic Considerations
ArticlesOct 16, 2025Learn More -
Establishment of a Novel Funnel Model for Evaluating Blood-Brain Barrier Penetration In Vitro
PostersSep 30, 2025Learn More -
In Vitro Metabolic Stability of Peptide Drugs Across Different Tissues
ArticlesSep 30, 2025Learn More -
Fast Biomimetic High-Performance Liquid Chromatography Method for Evaluating Human Plasma Protein Binding
PostersSep 30, 2025Learn More -
What Is Brain Microdialysis and Its Application in PK Studies for CNS Drugs
ArticlesSep 26, 2025Learn More -
Optimisation of an In Vitro Plated Monkey Hepatocyte Model and Comparative Metabolite Profiling of a GalNAc-Conjugated siRNA, siRNA01, in Monkey Liver Homogenate and Hepatocytes
PostersSep 26, 2025Learn More -
Biomimetic Chromatography Method to Estimate Human Plasma Protein Binding for Peptides
PostersSep 19, 2025Learn More -
Evaluation of Clearance Prediction Methods for Vepdegestrant (ARV-471) Using PBPK Modelling: Insights into PROTAC Clinical Pharmacokinetics
PostersSep 11, 2025Learn More -
Bioanalytical Strategy for Antibody-Drug Conjugates (ADCs) Based on Integrated Mass Spectrometry Bioanalysis Platform
PostersSep 11, 2025Learn More -
Novel Rat Intrathecal Catheterization Model for Direct Antisense Oligonucleotide (ASO) Drugs Delivery to the Central Nervous System
PostersAug 28, 2025Learn More -
Evaluating Oral Peptides' Gastrointestinal Absorption: Methods and Applications
ArticlesAug 28, 2025Learn More -
Advancing Novel Therapeutics with Innovative DMPK Strategies in Metabolism and Bioanalysis
WebinarsAug 22, 2025Learn More -
Optimizing Liposomes/LNPs: From Lipid Solvent Screening to Formulation Stability in PK Studies
ArticlesAug 22, 2025Learn More -
Radiolabeling Synthesis and ADME Profiling of GLP-1 Analogs: Strategies and Preclinical Insights
PostersAug 22, 2025Learn More -
Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS
PublicationsAug 15, 2025Learn More -
Decoding the Key Role of Plasma Protein Binding in Drug-Drug Interactions
ArticlesAug 15, 2025Learn More -
Is the Direct or Indirect Method the Ideal One for Evaluation of Blood to Plasma Ratio?
PostersAug 06, 2025Learn More -
An Efficient and Environmental Friendly Method for the Determination of Nucleoside Phosphate Compounds by Using LC-MS/MS
PostersAug 01, 2025Learn More -
Bioanalytical Strategy for Payload-Related Species of Antibody Drug Conjugates (ADCs) with LC-MS
PostersAug 01, 2025Learn More -
Antibody-Drug Conjugate (ADC) R&D Innovations and In Vitro ADME Research Considerations
ArticlesJul 24, 2025Learn More -
Solving the Peptide Puzzle: Strategies for Smarter Development
WebinarsJul 24, 2025Learn More -
An Integrated Radiolabeling and ADME Platform for Peptide Drugs
WebinarsJul 17, 2025Learn More -
mRNA Vaccines and Therapeutics: Advances in Modification, Delivery, Applications, and Analytical Strategies
ArticlesJul 17, 2025Learn More -
Optimization of Sample Pretreatment Methods for the Determination of an Oligonucleotide by Using LC-MS/MS
PostersJul 17, 2025Learn More -
Desorption Strategies in Peptide Formulation Preparation: Insights from In Vitro Adsorption (Non-Specific Binding) Assessment Experiments
PostersJul 17, 2025Learn More -
In Vitro Metabolic Stability Evaluation of Peptides
PostersJul 16, 2025Learn More -
Optimization and Assessment of Intrathecal (IT) Administration to Improve Drug Delivery to the CNS in Rats
PostersJul 11, 2025Learn More -
Rapid Screening and Characterization of Payload-Related Catabolites Derived from ADCs in In Vitro Models by UPLC-UV-HRMS
PostersJul 11, 2025Learn More -
A Robust LC-MS/MS Method for the Detection of Covalent Drugs in Mouse Blood
PostersJul 10, 2025Learn More -
An Ultra High-Throughput Method for 13C6-Fructose-6-Phosphate in Cells Using Acoustic Ejection Mass Spectrometry (AEMS)
PostersJul 04, 2025Learn More -
A Novel Validated LC-MS/MS Method for the Determination of Survodutide in Mouse Liver
PostersJul 04, 2025Learn More -
Exploring T-Cell Engagers (TCEs): Mechanism, Challenges, and Pharmacokinetic Considerations
ArticlesJul 04, 2025Learn More -
In Vitro Metabolism Methods for Oligonucleotides
White PapersJun 20, 2025Learn More -
How to Analyze and Separate Oligonucleotides and Active Metabolites Using LC-MS/MS
ArticlesJun 20, 2025Learn More -
Pharmacokinetic Comparison of Pemetrexed Administered via Lumbar Intrathecal vs.Cisterna Magna Intubation in Sprague-Dawley Rats
PostersJun 12, 2025Learn More -
Effective Intrathecal Injection/Catheterization in Rats for CNS Drugs: Challenges and Strategies
ArticlesJun 12, 2025Learn More -
Sample Chapter: Proteolysis-Targeting Chimeras (PROTACs) from Drug Metabolism and Pharmacokinetics: Frontiers, Strategies, and Applications
PublicationsJun 06, 2025Learn More -
Intrathecal Administration Techniques for CNS Delivery in Non-Human Primates:Practical Tools for Oligonucleotide Drug Pharmacokinetics
PostersJun 05, 2025Learn More -
Crossing the Blood-Brain Barrier for Central Nervous System Drugs: Challenges and Evaluation Strategies
BlogsJun 05, 2025Learn More -
Advancing In Vitro Metabolic Models and Metabolite Identification for Oligonucleotide Therapeutics
WebinarsJun 05, 2025Learn More -
Unlocking Reliable In Vitro Metabolic Models for Oligonucleotide Therapeutics with the Latest Publication on DMD
BlogsMay 28, 2025Learn More -
Intrathecal Administration: Breaking Barriers for Central Nervous System Drugs
VideosMay 28, 2025Learn More -
8 Commonly Used ADC Payloads and Their ADME and DDI Properties
ArticlesMay 22, 2025Learn More -
Discovery and Evaluation of Pyrazolo[3,4‑d]pyridazinone as a Potent and Orally Active Irreversible BTK Inhibitor
PublicationsMay 15, 2025Learn More -
Cyclic Peptides: FDA-Approved Drugs and Their Oral Bioavailability and Metabolic Stability Tactics
ArticlesMay 08, 2025Learn More -
Comparative Metabolism of a GalNAc-Conjugated siRNA, Inclisiran, Among Various In Vitro Systems and Correlations with In Vivo Metabolism in Rats
PublicationsMay 08, 2025Learn More -
2024 FDA-Approved Drug Highlights: Overview of Human Pharmacokinetics and DDI Profiles
ArticlesApr 29, 2025Learn More -
Detection and Characterization of In Vitro Payload-Containing Catabolites of Noncleavable Antibody-Drug Conjugates by High-Resolution Mass Spectrometry and Multiple Data Mining Tools
PublicationsApr 28, 2025Learn More -
Metabolic disposition of [14C]-abivertinib, an epidermal growth factor receptor tyrosine kinase inhibitor: Role of glutathione conjugation
PublicationsApr 25, 2025Learn More
Related Services
-
In Vitro ADME ServicesLearn More -
In Vivo PharmacokineticsLearn More
-
MetID (Metabolite Profiling and Identification)Learn More
-
Radiolabeled In Vivo ADME StudyLearn More
-
DMPK BioanalysisLearn More
-
Novel Drug Modalities DMPK Enabling PlatformsLearn More
-
Therapeutic Areas DMPK Enabling PlatformsLearn More
Stay Connected
Keep up with the latest news and insights.
