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8 Commonly Used ADC Payloads and Their ADME and DDI Properties

Discovery and Evaluation of Pyrazolo[3,4‑d]pyridazinone as a Potent and Orally Active Irreversible BTK Inhibitor

Internal Standards in LC−MS Bioanalysis: Which, When, and How

Cyclic Peptides: FDA-Approved Drugs and Their Oral Bioavailability and Metabolic Stability Tactics

Comparative Metabolism of a GalNAc-Conjugated siRNA, Inclisiran, Among Various In Vitro Systems and Correlations with In Vivo Metabolism in Rats

2024 FDA-Approved Drug Highlights: Overview of Human Pharmacokinetics and DDI Profiles

Detection and Characterization of In Vitro Payload-Containing Catabolites of Noncleavable Antibody-Drug Conjugates by High-Resolution Mass Spectrometry and Multiple Data Mining Tools

Metabolic disposition of [¹⁴C]-abivertinib, an epidermal growth factor receptor tyrosine kinase inhibitor: Role of glutathione conjugation

Immunogenicity Testing: Definition, Guidelines, and Anti-Drug Antibody Detection

AAPS 2025 PHarmSCi 360

C&EN Webinars | Integrated Bioanalytical Platform and DMPK Strategies for Antibody-Drug Conjugates

Stay Connected

Resources

8 Commonly Used ADC Payloads and Their ADME and DDI Properties

Discovery and Evaluation of Pyrazolo[3,4‑d]pyridazinone as a Potent and Orally Active Irreversible BTK Inhibitor

Internal Standards in LC−MS Bioanalysis: Which, When, and How

Cyclic Peptides: FDA-Approved Drugs and Their Oral Bioavailability and Metabolic Stability Tactics

Comparative Metabolism of a GalNAc-Conjugated siRNA, Inclisiran, Among Various In Vitro Systems and Correlations with In Vivo Metabolism in Rats

2024 FDA-Approved Drug Highlights: Overview of Human Pharmacokinetics and DDI Profiles

Detection and Characterization of In Vitro Payload-Containing Catabolites of Noncleavable Antibody-Drug Conjugates by High-Resolution Mass Spectrometry and Multiple Data Mining Tools

Metabolic disposition of [14C]-abivertinib, an epidermal growth factor receptor tyrosine kinase inhibitor: Role of glutathione conjugation

Immunogenicity Testing: Definition, Guidelines, and Anti-Drug Antibody Detection

AAPS 2025 PHarmSCi 360

C&EN Webinars | Integrated Bioanalytical Platform and DMPK Strategies for Antibody-Drug Conjugates

Stay Connected

Metabolic disposition of [¹⁴C]-abivertinib, an epidermal growth factor receptor tyrosine kinase inhibitor: Role of glutathione conjugation